Key Research Articles
Rona, G., Miwatani-Minter, B., Zhang, Q., Goldberg, H. V., Kerzhnerman, M. A., Howard, J. B., Simoneschi, D., Lane, E., Hobbs, J. W., Sassani, E., Wang, A. A., Keegan, S., Laverty, D. J., Piett, C. G., Pongor, L. S., Xu, M. L., Andrade, J., Thomas, A., Sicinski, P., Askenazi, M., Ueberheide, B., Fenyö, D., Nagel, Z. D. & Pagano, M. CDK-independent role of D-type cyclins in regulating DNA mismatch repair. Mol Cell (2024).
Zhang, Q., Kerzhnerman, M. A., García-Vázquez, N., Rona, G. Visualizing Single-Stranded DNA Foci in the G1 Phase of the Cell Cycle. J. Vis. Exp (2023).
Rona, G., Zeke, A., Miwatani-Minter, B., de Vries, M., Kaur, R., Schinlever, A., Garcia, S. F., Goldberg, H. V., Wang, H., Hinds, T. R., Bailly, F., Zheng, N., Cotelle, P., Desmaele, D., Landau, N. R., Dittmann, M. & Pagano, M. The NSP14/NSP10 RNA repair complex as a Pan-coronavirus therapeutic target. Cell Death Differ 29, 285-292 (2022).
Simoneschi, D., Rona, G., Zhou, N., Jeong, Y. T., Jiang, S., Milletti, G., Arbini, A. A., O'Sullivan, A., Wang, A. A., Nithikasem, S., Keegan, S., Siu, Y., Cianfanelli, V., Maiani, E., Nazio, F., Cecconi, F., Boccalatte, F., Fenyo, D., Jones, D. R., Busino, L. & Pagano, M. CRL4(AMBRA1) is a master regulator of D-type cyclins. Nature 592, 789-793 (2021).
Miwatani-Minter, B. & Rona, G. Laser Micro-Irradiation to Study DNA Recruitment During S Phase. J Vis Exp (2021).
Maiani, E., Milletti, G., Nazio, F., Holdgaard, S. G., Bartkova, J., Rizza, S., Cianfanelli, V., Lorente, M., Simoneschi, D., Di Marco, M., D'Acunzo, P., Di Leo, L., Rasmussen, R., Montagna, C., Raciti, M., De Stefanis, C., Gabicagogeascoa, E., Rona, G., Salvador, N., Pupo, E., Merchut-Maya, J. M., Daniel, C. J., Carinci, M., Cesarini, V., O'Sullivan, A., Jeong, Y. T., Bordi, M., Russo, F., Campello, S., Gallo, A., Filomeni, G., Lanzetti, L., Sears, R. C., Hamerlik, P., Bartolazzi, A., Hynds, R. E., Pearce, D. R., Swanton, C., Pagano, M., Velasco, G., Papaleo, E., De Zio, D., Maya-Mendoza, A., Locatelli, F., Bartek, J. & Cecconi, F. AMBRA1 regulates cyclin D to guard S-phase entry and genomic integrity. Nature 592, 799-803 (2021).
Palinkas, H. L., Bekesi, A., Rona, G., Pongor, L., Papp, G., Tihanyi, G., Holub, E., Poti, A., Gemma, C., Ali, S., Morten, M. J., Rothenberg, E., Pagano, M., Szuts, D., Gyorffy, B. & Vertessy, B. G. Genome-wide alterations of uracil distribution patterns in human DNA upon chemotherapeutic treatments. Elife 9 (2020).
Rona, G., Roberti, D., Yin, Y., Pagan, J. K., Homer, H., Sassani, E., Zeke, A., Busino, L., Rothenberg, E. & Pagano, M. PARP1-dependent recruitment of the FBXL10-RNF68-RNF2 ubiquitin ligase to sites of DNA damage controls H2A.Z loading. Elife 7 (2018).
Rona, G., Scheer, I., Nagy, K., Palinkas, H. L., Tihanyi, G., Borsos, M., Bekesi, A. & Vertessy, B. G. Detection of uracil within DNA using a sensitive labeling method for in vitro and cellular applications. Nucleic Acids Res 44, e28 (2016).
Dankert, J. F., Rona, G., Clijsters, L., Geter, P., Skaar, J. R., Bermudez-Hernandez, K., Sassani, E., Fenyo, D., Ueberheide, B., Schneider, R. & Pagano, M. Cyclin F-Mediated Degradation of SLBP Limits H2A.X Accumulation and Apoptosis upon Genotoxic Stress in G2. Mol Cell 64, 507-519 (2016).
Rona, G., Borsos, M., Ellis, J. J., Mehdi, A. M., Christie, M., Kornyei, Z., Neubrandt, M., Toth, J., Bozoky, Z., Buday, L., Madarasz, E., Boden, M., Kobe, B. & Vertessy, B. G. Dynamics of re-constitution of the human nuclear proteome after cell division is regulated by NLS-adjacent phosphorylation. Cell Cycle 13, 3551-3564 (2014).
Muha, V., Horvath, A., Bekesi, A., Pukancsik, M., Hodoscsek, B., Merenyi, G., Rona, G., Batki, J., Kiss, I., Jankovics, F., Vilmos, P., Erdelyi, M. & Vertessy, B. G. Uracil-containing DNA in Drosophila: stability, stage-specific accumulation, and developmental involvement. PLoS Genet 8, e1002738 (2012).